Septal Perforation

Septal Perforations, Repair & Nosebleeds in HHT

Septal Perforations are late complications of chronic nose bleeds in patients with Hereditary Hemorrhagic Telangiectasia (HHT), also known as Osler-Weber-Rendu Disease. Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic disease characterized by aberrant overgrowth and proliferation (dysplasia) of vascular tissue known as telangiectasias and arteriovenous malformations (AVMs) within mucosal membranes of the body. HHT presents with …

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Hereditary Hemorrhagic Telangiectasia: Early Diagnosis of Nasal Mucosal Telangiectasias

Hereditary Hemorrhagic Telangiectasia (HHT) is a hereditary disorder characterized by abnormal clusters of fragile capillaries that bleed with minimal agitation. Telangiectasias, commonly involve the nasal mucosa causing recurrent nosebleeds that may be severe enough to require hospitalization, surgical cauterization as well as blood and/or iron transfusions. Download Article PDF Click here to learn more.

Hereditary Hemorrhagic Telangiectasia: Diagnosis and Treatment of Epistaxis

Hereditary Hemorrhagic Telangiectasia (HHT) is a hereditary disorder characterized by abnormal clusters of weak bulging capillaries that bleed with little to no trauma or insult. They most commonly affect the nasal mucosa, but also involve the gut, skin, brain and lungs as well. Clinically patients most commonly report a history of recurrent nosebleeds (epistaxis) before …

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Wegener’s Granulomatosis: Autoimmune Disease and Multi-Focal Septal Perforation

Autoimmune disorders are characterized by antibodies that turn against the body’s own normal tissues. While typical antibodies fight off viruses, bacteria, and cancer cells, pathological autoantibodies directed against the bodies own tissues can result in complex autoimmune disorders. Wegener’s granulomatosis is an autoimmune disorder that attacks blood vessels throughout the body. Download article in PDF …

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Mega-Perforation: Pushing the Limits of Septal Perforation Repair

We have coined the term ‘Mega-perforation’ to refer to a septal perforation that approaches the limits of reparability. Typically perforations greater than 3.0-3.5cm and/or greater than 75% of the anterior septum size fall into this category. The “watch and wait” approach to managing any septal perforations is typically the wrong approach because perforations increase in …

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